Icars scale. Jan 28, 2013 · Materials and methods.

Thus, a clinical Oct 20, 2006 · The International Cooperative Ataxia Rating Scale (ICARS) was developed to assess pharmacotherapies in ataxia, 5 and has good inter‐rater reliability. Feb 12, 1997 · However, the scales used by trialists were all different and were of two types: a first type consisted in of sole global evaluation (Sobue et al. , 1997, Schmitz-Hubsch et al. Jan 31, 2006 · This study evaluated metric properties of the International Cooperative Ataxia Rating Scale (ICARS) in 156 SCA patients and 8 controls. We aim to improve skills and competencies around implementation and intervention research and the scale-up of ICARS co-developed solutions to tackle AMR. , 2009, du Montcel et Feb 12, 1997 · DOI: 10. 2017;18:135–40. , 1986; Trouillas et The International Cooperative Ataxia Rating Scale (ICARS) is an outcome measure that was created in 1997 by the Committee of the World Federation of Neurology with the goal of standardizing the quantification of impairment due to cerebellar ataxia. 2 of 100,000 people. The event, co-funded by ICARS and other partners, focused on Africa’s response to Antimicrobial Resistance: Accelerating One Health National Action Plans implementation for the next 5 years. Sep 15, 2009 · The modified International Cooperative Ataxia Rating Scale and Brief Ataxia Rating Scale have an assigned category of eye movement deficits; however, the assessment is not detailed [7]. 1 Several scales have been developed to rate ataxias. We evaluated reliability (internal consistency), criterion-related validity and internal construct validity of ICARS for the first time in patients with focal cerebellar lesions Dec 19, 2023 · International Cooperative Ataxia Rating Scale（ICARS）の評価用紙については、「埼玉県難病患者医療支援事業. ICARS provides funding and guidance to address these constraints and challenges through co-development of feasible, cost-effective ICARS aims to fill gaps identified in relation to the activities performed under pillars 1 and 2 by supporting targeted knowledge exchange and training. Results: SARA scale was translated into Brazilian version with adequate internal consistence, but a significant correlation between ICARS and SARA was not found. The posture and gait Mar 15, 2008 · The International Cooperative Ataxia Rating Scale (ICARS) is widely used as a scale for assessing the severity of cerebellar ataxia and therapeutic effects. Dec 30, 2011 · The International Cooperative Ataxia Rating Scale (ICARS) has been widely used as a tool for assessing the severity and treatment effectiveness of cerebellar ataxia. Method The process involved six The international cooperative ataxia rating scale (ICARS) 11 graded ataxia based on four domains: posture and gait, kinetic function, speech, and oculomotor disorder. The purpose of this study was to investigate the validity and reliability of the Korean-translated version of the ICARS. It consists of 19 items grouped into four subscales that contribute to a total score of 100 points. WALKING CAPACITIES observed during a 10 meter test including a half-turn, near a wall, at about 1,5meter. There are several quality characteristics for clinical scales: The inter-rater reliability covers the variation of the ratings on the same subject between independent investigators while test-retest reliability describes the concordance between the ratings of an individual Nov 29, 2023 · Salcı Y, Fil A, Keklicek H, Çetin B, Armutlu K, Dolgun A, et al. Cross-sectional ICARS data were collected from 603 patients with Friedreich’s ataxia from Europe, North America and Australia between 2005 and 2009 by investigators experienced in the use of the ICARS as originally described (Trouillas et al. Methods: The steps of this study were forward translation, translation synthesis, backward translation, expert committee meeting, preliminary pilot testing and final assessment. 1997). We then used the statistics package R to find a five‐test subset in MICARS that would correlate best with the total MICARS score. However, this scale comprises several items; thus Jun 10, 2016 · The worldwide prevalence of late onset ataxia is approximately 10. 神経難病の理解1」の 14 ページに参考資料がございます。 The International Cooperative Ataxia Rating Scale (ICARS) is also frequently used in clinical practice to assess cerebellar symptoms, but it has not been available in Brazilian Portuguese. We found a lack of correlation between the total SODA score and the total International Cooperative Ataxia Rating Scale (ICARS), Scale for Assessment and Rating of Ataxia (SARA), or Brief Ataxia Rating Scale (BARS). Aug 19, 2005 · This study evaluated the psychometric properties of the International Cooperative Ataxia Rating Scale (ICARS), a commonly used clinician-rated measure, in Friedreich's ataxia (FRDA). Jun 1, 2012 · International Cooperative Ataxia Rating Scale [3] Scale Description The ICARS i s a semiqua ntitative 1 00-point scale cons isting of 19 items, divi ded into four unequa lly. It has recently been reported that age-appropriate developing children show physiologically higher scores than adults in ARS up to an age of 12 years [ 16 , 17 ]. 2005; Schmitz-Hübsch et al. で最近は、ICARSから8項目（歩行、立位、座位、言語障害、指追い試験、鼻指試験、手の回内・回外運動、踵脛試験）に項目を絞った SARA(scale for the assessment and rating of ataxia) という評価法が用いられるようになっている。 The aim of our study was to investigate the reliability and validity of the Turkish version of the International Cooperative Ataxia Rating Scale (ICARS) and Scale for the Assessment and Rating of Ataxia (SARA), which are widely used in ataxia evaluation in the context of other cerebellar diseases. However, no standardized Sep 29, 2017 · The aim of our study was to investigate the reliability and validity of the Turkish version of the International Cooperative Ataxia Rating Scale (ICARS) and Scale for the Assessment and Rating of Ataxia (SARA), which are widely used in ataxia evaluation in the context of other cerebellar diseases. Interpretation: In children with FRDA, ataxia scales based on ICARS are confounded by muscle weakness. 1 Quantifying severity and tracking changes in the clinical symptom profile is challenging, and usually focuses Aug 21, 2007 · Reliability and validity of the semiquantitative International Cooperative Ataxia Rating Scale (ICARS) has recently been examined in patients with degenerative ataxias. It offers a semiquantitative quantification of cerebellar ataxia with special emphasis on the different components of ataxia: While static functions are attributed to the vermis and anterior lobe (posture and gait), limb ataxia (kinetic functions) is thought to result from impairment of the Jul 17, 2013 · There are several clinical ataxia rating scales including the International Cooperative Ataxia Rating Scale (ICARS), the Friedreich Ataxia Rating Scale (FARS) and the Scale for the Assessment and Rating of Ataxia (SARA) (Trouillas et al. We do this by co-developing tailored solutions with LMIC governments and researchers, who then implement them on the ground using ICARS funding and expertise, building on AMR National Action Plans. 10. Polynomial analysis with one phase decay trend line was used to form plots of total scores related to age. ICARS completion requires at least 20 minutes ( Schmitz-Hübsch et al. INTERNATIONAL CO-OPERATIVE ATAXIA RATING SCALE I: POSTURE AND GAIT DISTURBANCE SCORE: 1. All three scales tend to measure motor aspects of Objective: To investigate the related factors of international cooperative ataxia rating scale (ICARS) and scale for the assessment and rating of ataxia scores (SARA) in patients with spinocerebellar ataxia type 3/Machado-Joseph disease. Three neurologists independently rated videotaped ICARS examinations of 22 subjects with genetically Jan 1, 2006 · Request PDF | On Jan 1, 2006, K. Friedreich's ataxia (FRDA) is a progressive neurological disease characterized by gait and limb ataxia, dysarthria, loss of reflexes, proprioceptive dysfunction, and muscle weakness, as well as non‐neurological features including cardiomyopathy, diabetes, and scoliosis. See full list on physio-pedia. This study set out to characterize the frequency and pattern of clinical signs of ACD in an alcoholic group using the International Cooperative Ataxia Rating Scale (ICARS). May 7, 2015 · Excellent construct validity of SARA items with International Cooperative Ataxia Rating Scale (ICARS) (r = 0. These ataxia rating scales showed adequate psychometric proprieties represented with feasibility, acceptability We aimed to translate, adapt and validate the International Cooperative Ataxia Rating Scale (ICARS) into Brazilian Portuguese. 1 Several scales have been developed to rate ataxias. Ninety-six patients with a molecular genetic diagnosis of FRDA were rated using three different clinical scales, the FRDA Rating Scale (FARS), the International Cooperative Ataxia Rating Scale (ICARS), and SARA. icars を算出することで、運動失調の経時変化や治療法の効果判定の指標となる。 運動機能面では、改善すべき運動失調を明確にすることで効果的なリハビリテーションプログラムの立案に役立ち、歩行補助具や福祉用具の選択に反映できる。 May 1, 2006 · Using the International Cooperative Ataxia Rating Scale (ICARS), an assessment with a minimal detectable change score of 1. , 1997) or study personnel specifically trained. Authors acknowledged that cerebellar signs may occur within a more complex syndrome in ataxia disorders, but selected items according to their assumed specificity for ataxia. BARS scale is based on a modified form of the ICARS scale and is valid, reliable and sufficiently fast for clinical purposes. Methods: We compared the performance of 49 alcoholics and 29 control participants. Mar 25, 2022 · The relation between interview responses and the International Cooperative Ataxia Rating Scale (ICARS) was explored to examine how well patient self-report tracked with clinical observational measures. This treatment led to a moderate clinical improvement of ataxia as assessed with ICARS 8 (pre-and post-treatment scores, 15 days after the onset of the treatment, are given in Table 1) and This study evaluated the psychometric properties of the International Cooperative Ataxia Rating Scale (ICARS), a commonly used clinician-rated measure, in Friedreich’s ataxia (FRDA). , 2012) The International Cooperative Ataxia Rating Scale (ICARS) was introduced in 1997 to provide a standardised clinical rating system for ataxia treatment trials. It consists of four subscales, gait/posture, kinetic Apr 5, 2023 · The International Cooperative Ataxia Rating Scale (ICARS) was the first ataxia scale. Six randomized controlled trials involving 175 patients were included in the analysis. 6 years; mean disease duration, 5. ICARS has been used in some genetic diseases such as Friedreich ataxia, coenzyme Q deficiency and others [14, 15]. Apr 1, 2010 · The International Cooperative Ataxia Rating Scale (ICARS) is widely used as a scale for the assessment of the severity of cerebellar ataxia. There is apparently no clear advantage of one in Oct 26, 2015 · The International Cooperative Ataxia Rating Scale (ICARS) is a neurologist-completed scale developed to assess cerebellar ataxia , that has been recently validated in healthy children above 4 years of age . However, the daily use of this scale in ataxic patients is difficult due to its many assessment items. Calidad de aire aceptable. May 9, 2012 · Request PDF | Characterization of Cerebellar Ataxia in Chronic Alcoholics Using the International Cooperative Ataxia Rating Scale (ICARS) | Alcoholism is the most common cause of cerebellar Mar 21, 2023 · Several clinical scales have been validated for the assessment of disease severity and progression in cerebellar disease. 1–3 The ICARS is composed of four clinical sub-scores involving the following specific aspects: posture and gait Nov 20, 2003 · We assessed the inter-rater reliability of the 100-point International Cooperative Ataxia Rating Scale (ICARS). At ICARS, our mission is to partner with Low- and Middle-income countries (LMICs) in their efforts to reduce drug-resistant infections. SARA is a clinical scale developed by Schmitz-Hübsch et al which assesses a range of different impairments in cerebellar ataxia. Symptom category clusters were also explored in order to help characterize symptom profiles, which could inform prognostication. Mult Scler Relat Disord. However, the application of this scale in daily examinations of ataxic patients is limited due to the large number of items to be evaluated [1]. Jan 28, 2013 · Materials and methods. The ICARS was developed by Trouillas et al. Nov 1, 2017 · Currently, different performance-based clinical scales are available for ataxia rating; the most widely used are the International Cooperative Ataxia Rating Scale (ICARS) and the Scale for the Assessment and Rating of Ataxia (SARA) (Trouillas et al. Nov 17, 2023 · Major efficacy outcomes were assessed, including International Cooperative Ataxia Rating Scale (ICARS) scores, Scale for the Assessment and Rating of Ataxia (SARA) scores, and ICARS subscale scores. ICARS was found to be a reliable scale satisfying accepted criteria for interrater reliability, test–retest reliability, and internal consistency. 0: normal 1: almost normal naturally, but unable to walk with feet in tandem position 2: Walking without support, but clearly abnormal and irregular Sep 1, 2017 · Recently, the International Cooperative Ataxia Rating Scale (ICARS) and the Scale for the Assessment and Rating of Ataxia (SARA), which are consistently used in cerebellar neurodegenerative Apr 24, 2023 · Background/objective The scale for the assessment and rating of ataxia (SARA) is a feasible assessment for the classification and evaluation of therapeutic interventions. Three neurologists independently rated videotaped ICARS examinations of 22 subjects with genetically determined ataxias (spinocerebellar ataxia [SCA] Type 1 in 11; SCA Type 2 in 1; Friedreich's ataxia in 10) and 4 controls. Objective [edit | edit source]. Oct 1, 2011 · Semiquantitative Ataxia Scales International Cooperative Ataxia Rating Scale []Scale Description. Scale SARA ICARS UMSARS FARS Numbers of items 8 19 30 36 Number of concepts (Different) Dec 5, 2022 · The scales are: scale for assessment and rating of ataxia (SARA) , international cooperative ataxia rating scales (ICARS) , Friedreich’s ataxia rating scale (FARS) , and unified multiple system atrophy rating scale (UMSARS) . The relative contributions of demographic and alcohol consumption variables to ICARS It was applied to 30 patients. They are validated instruments used widely for Sep 6, 2002 · Cross-sectional analysis of internal consistency, factor structure, and correlation with parkinsonism severity (Unified Parkinson's Disease Rating Scale [UPDRS] III) of the ICARS, in 50 unselected MSA patients (mean age, 67. Friedreich's ataxia (FRDA) is a progressive neurological disease characterized by gait and limb ataxia, dysarthria, loss of reflexes, proprioceptive dysfunction, and muscle weakness, as well as non-neurological features including cardiomyopathy, diabetes, and scoliosis. Sep 15, 2009 · SARA is limited to eight items and can be performed rapidly. The International Cerebellar Ataxia Rating Scale (ICARS) and the Scale for Assessment and Rating of Ataxia (SARA) are the two best-known, validated, and broadly used rating scales. 1016/S0022-510X(96)00231-6 Corpus ID: 45632293; International Cooperative Ataxia Rating Scale for pharmacological assessment of the cerebellar syndrome @article{Trouillas1997InternationalCA, title={International Cooperative Ataxia Rating Scale for pharmacological assessment of the cerebellar syndrome}, author={Paul Trouillas and Tetsuya Takayanagi and Mark Hallett and Robert D. We aimed to translate, adapt and validate the International Cooperative Ataxia Rating Scale (ICARS) into Brazilian Portuguese. Buena calidad de aire. Kanai and others published Interrater reliability and internal consistency of the international cooperative ataxia rating scale (ICARS) | Find, read and cite all Nov 17, 2022 · We applied the modified Friedreich Ataxia Rating Scale (mFARS), the Scale for the Assessment and Rating of Ataxia (SARA), and the International Cooperative Ataxia Rating Scale (ICARS) to a large Scales are used to understand better its natural history and evaluate properly drug efficacy in clinical trials. One, the Scale for the Assessment and Rating of Ataxia (SARA) 10,11 focuses on a compact structure and quick administration. Mar 15, 2008 · The International Cooperative Ataxia Rating Scale (ICARS) is widely used as a scale for assessing the severity of cerebellar ataxia and therapeutic effects. Three neurologists independently rated videotaped ICARS examinations of 22 subjects with genetically determined ataxias (spinocerebellar ataxia [SCA] Type 1 in 11; SCA Type 2 in 1; Friedre … Dec 31, 2017 · The International Cooperative Ataxia Rating Scale (ICARS) was published in 1997 as a clinical rating scale for use in ataxia disorders. Methods: A total of 126 SCA3/MJD patients were assessed by ICARS and SARA. , 1981), while a second type involved the addition of the points of several subtests, with a more elevated maximum final score (Filla et al. 96 points [18], a 4-week cycling program caused an improvement of only 2. ICARS (MX) representa los niveles de calidad del aire según las siguientes categorías de salud: Categoría. Introduction: The clinical assessment of patients with ataxias requires reliable scales. 1 Quantifying severity and tracking changes in the clinical symptom profile is challenging, and usually As Executive Director, Dr. The modified International Cooperative Ataxia Rating Scale and Brief Ataxia Rating Scale have an assigned category of eye movement deficits; however, the assessment is not detailed . We first modified the International Cooperative Ataxia Rating Scale (ICARS) by adding seven ataxia test … Mar 14, 2024 · Home / 2024 / Ensuring Successful Implementation and Scale-up of the ICARS-Supported Projects in Georgia Dr Robert Skov, Dr Gloria Cordoba and Dr Mabel De Leo from the ICARS Science Team visited Georgia to meet two of the ICARS-supported project teams and engage with national stakeholders. Thus, a In 1997, ICARS had been developed and assessed as a clinical rating scale for cerebellar disorders. 3 Accordingly, Schmitz-Hübsch et al. In addition to SARA, we applied the International Cooperative Ataxia Rating Scale (ICARS) in all subjects. 1–3 The ICARS is composed of four clinical sub-scores involving the following specific aspects: posture and gait, limb Dec 5, 2022 · and ICF indicators for the included ataxia rating scale. , 1983; Kark et al. The scale is made up of 8 items related to gait, stance, sitting, speech, finger-chase test, nose-finger test, fast alternating movements and heel-shin test. People with confirmed FRDA were assessed by using the ICARS. This framework describes the phases of the application process (Figure 2), which includes: Expression of Interest (phase 1), Concept Note (phase 2) and Project Proposal (phase 3). Dec 20, 2023 · The Scale for Assessment of Rating of Ataxia (SARA) comprises eight subscales based on the semi-quantitative assessment of cerebellar ataxia. All three scales tend to measure motor aspects of cerebellar dysfunction including ataxia of stance, gait and Aug 26, 2022 · The two most commonly used scales are the International Cooperative Ataxia Rating Scale (ICARS) and the Scale for Assessment and Rating of Ataxia (SARA) [13,14,15]. 難病患者支援マニュアル2. Dec 15, 2022 · Our validation studies revealed that the scale reliably measured the extent of saccade abnormalities and nystagmus. ICARS has been widely used in observational studies as well as in interventional trials. , 2006b ). However, the application of this scale in daily examinations of ataxic patients is limited due to the large number of items to be evaluated [1] . People with confirmed FRDA were assessed by using the ICARS. Sujith J Chandy leads ICARS’ science- and operations teams and works closely with the Board of Directors. Nov 16, 2022 · Introduction. com Oct 6, 2022 · In July 2022, more than 140 participants from 30 countries attended the annual ReAct Africa and South Centre conference in Lusaka, Zambia. Nov 25, 2016 · Several clinical scales have been validated for the assessment of disease severity and progression in cerebellar disease. 2006). , 2009, du Montcel et Jan 7, 2014 · Ataxia rating scales the International Cooperative Ataxia Rating Scale (ICARS), the Scale for Assessment and Rating of Ataxia (SARA), and the Brief Ataxia Rating Scale (BARS) and the nine-hole PEG-board test related to age. The weight of each symptomatologic compartment has been carefully designed. 5 years), 50 age-matched and disease duration-matched Parkinson' disease (PD) patients Dec 20, 2022 · The International Cooperative Ataxia Rating Scale (ICARS) is a semiquantitative clinical scale for ataxia that is widely used in numerous countries. 6 It has since been used for this purpose by several groups7–9 and has also been used to assess cerebellar signs in multiple system atrophy,10 although its inter-rater reliability has Linear regression analysis was employed to test the associations between retinal parameters and age, disease duration, CAG repeats, and SARA (Scale of the Assessment and Rating of Ataxia) and ICARS (International Cooperative Ataxia Rating Scale) scores in SCA3. Concurrently Under the condition of persistently absent sensory evoked potentials, leg ICARS subscores in the FRDA group appeared to be positively associated with leg muscle force until a maximal plateau level of ICARS subscores was reached. ICARS also assists policing partners with major crime scenes through aerial (drone) photography and surveying/3D Laser scanning to create scale diagrams. Current ataxia rating scales are cumbersome and not designed for clinical practice. We assessed the inter‐rater reliability of the 100‐point International Cooperative Ataxia Rating Scale (ICARS). 1 Quantifying severity and tracking changes in the clinical symptom profile is challenging, and usually focuses We assessed the inter‐rater reliability of the 100‐point International Cooperative Ataxia Rating Scale (ICARS). Nov 20, 2003 · We assessed the inter-rater reliability of the 100-point International Cooperative Ataxia Rating Scale (ICARS). Methods: The steps of this study were forward translation, translation synthesis, backward translation, expert committee meeting, preliminary pilot testing and final assessment Feb 12, 1997 · The scale proposed involves a compartimentalized quantification of postural and stance disorders, limb ataxia, dysarthria and oculomotor disorders, in order that a subscore concerning these symptoms may be separately studied. There are several quality characteristics for clinical scales: The interrater reliability covers the variation of the ratings on the same subject between independent investigators while test–retest reliability describes the concordance between the ratings of an individual Feb 1, 2004 · The ICARS exhibits very high inter‐rater reliability even without prior observer standardisation and is sensitive to a range of ataxia severities from very mild to severe. Jan 28, 2013 · The International Cooperative Ataxia Rating Scale (ICARS) was developed and validated to assess symptoms of ataxia, and it has been used frequently in Friedreich’s ataxia clinical studies. adults, the International Cooperative Ataxia Rating Scale (ICARS) is a commonly used evaluation, initially designed for longitudinal assessment of pharmacological therapies in patients with cerebellar ataxia. 1997; Subramony et al. At the moment, ICARS is financing and engaging in the co-development of small scale demonstration research projects with a typical duration of 2-3 years. Longitudinal We first modified the International Cooperative Ataxia Rating Scale (ICARS) by adding seven ataxia tests (modified ICARS, or MICARS), and observed only minimally increased scores. The scale was devised by an expert ad hoc committee in 1997 as a first international standard for the clinical rating of ataxia (Trouillas et al. Currier Many LMIC governments are highly committed to addressing AMR but have severe resource and capacity constraints and thus require substantial development assistance to sustainably implement their NAPs at scale. Oct 29, 2019 · A first widely accepted such instrument was the International Cooperative Ataxia Rating Scale (ICARS), 2 but its use in clinical studies in FRDA 3,– 7 has diminished 8,9 in favor of advanced developments. 938) (Saute et al. , 1997 ). This treatment led to a moderate clinical improvement of ataxia as assessed with ICARS 8 (pre-and post-treatment scores, 15 days after the onset of the treatment, are given in Table 1) and Jan 1, 2018 · International cooperative ataxia rating scale In 1997, ICARS had originally been developed and assessed as a clinical rating scale for cerebellar disorders in general ( Trouillas et al. ICARS members provide expert testimony in court to support major investigations. The ICARS is a semiquantitative 100-point scale consisting of 19 items, divided into four unequally weighted sub-scores: posture and gait disturbance (seven items, 34 points); limb kinetic function (seven items, 52 points); speech disorder (two items, eight points); and oculomotor disorder (three We assessed the inter-rater reliability of the 100-point International Cooperative Ataxia Rating Scale (ICARS). Prior to joining ICARS, Sujith was a Professor in Clinical Pharmacology at Christian Medical College, Vellore, India, and Director of ReAct Asia Pacific. 6 The Functional Independence Measure (FIM) 7 and the Modified Barthel Index (MBI) 8 examine the assistance required to complete ADLs. 11 11. 2005; Schmitz-H€ubsch et al. , 1988; Bonnet et al. SARA and ICARS scales have been the most studied and validated so far. Sep 15, 2009 · To develop a brief ataxia rating scale (BARS) for use by movement disorder specialists and general neurologists. Jan 19, 2021 · SCA3 patients with GEN had higher scores of International Cooperative Ataxia Rating Scale (ICARS-IV) and total ICARS, and longer length of CAG repeat than patients without GEN. Validity and reliability of the International Cooperative Ataxia Rating Scale (ICARS) and the Scale for the Assessment and Rating of Ataxia (SARA) in multiple sclerosis patients with ataxia. 953) Excellent construct validity of SARA with Friedreich’s Ataxia rating Scale (FARS) (r = 0. The relation between ICARS or Trouillas P, Takayanagi T, Hallett M, Currier RD, Subramony SH, Wessel K, Bryer A, Diener HC, Massaquoi S, Gomez CM, Coutinho P, Ben Hamida M, Campanella G, Filla A, Schut L, Timann D, Honnorat J, Nighoghossian N, Manyam B. , 2006a, Lynch et al. This study evaluated the psychometric properties of the International Cooperative Ataxia Rating Scale (ICARS), a commonly used clinician-rated measure, in Friedreich's ataxia (FRDA). In order to provide access to the SARA in German, the aim of this work was to translate the SARA into German and to adapt it according to international guidelines for German-speaking countries. . , 2006, Schmahmann et al. Jun 5, 2009 · Both in children and adults, the International Cooperative Ataxia Rating Scale (ICARS) is a commonly used evaluation, initially designed for longitudinal assessment of pharmacological therapies in patients with cerebellar ataxia. ICARS, international cooperative ataxia rating scales; FARS, Friedreich’s ataxia rating scale; SARA, scale for assessment and rating ataxia; UMSARS, unified multiple system atrophy rating scale. International Cooperative Ataxia Rating Scale for pharmacological assessment of the cerebellar syndrome. SCA3 patients with slowing of saccades had a longer disease duration, higher scores of ICARS-I, ICARS-II, total ICARS and SARA than patients without slowing of saccades. recently proposed the Scale for the International Cooperative Ataxia Rating Scale (ICARS), the Friedreich Ataxia Rating Scale (FARS) and the Scale for the Assessment and Rating of Ataxia (SARA) (Trouillas et al. df qf it mm hf re ua ao vu fk